Complete combinatorial mutational enumeration of a protein functional site enables sequence-landscape mapping and identifies highly-mutated variants that retain activity

Mireia Solà Colom, Jelena Vučinić, Jared Adolf-Bryfogle, James Bowman, Sébastien Verel, Isabelle Moczygemba, Thomas Schiex, David SIMONCINI, Christopher Bahl
août 2024
HAL Citation DOI
Type (tous)
Article de revue
Publication
Protein Science
highly-mutated variants sequence-landscape