CarthaGène is a genetic/radiated hybrid mapping software. CarthaGene looks for multiple populations maximum likelihood consensus maps using a fast EM algorithm for maximum likelihood estimation and powerful ordering algorithms. CarthaGène:

CarthaGène has been developped in tight interaction with biologists. In particular, it has been jointly extended and used with D. Milan from the Laboratoire de Génétique Cellulaire to map the INRA-University of Minnesota porcine Radiation Hybrid (IMpRH) panel and benefited from contributors such as W. Snelling (USDA), C. Nelson (Kansas State Univ.), B. Servin and T. Faraut (LGC, INRA).

CarthaGène consists of three interfaces. Each one of them produces services of different levels. The graphical interface (see snapshots) allows an easy and immediate use of the available functions. It proposes also a graphical representation of the results. The shell, built as an extension of the scripting language Tcl, provides an effective user interface, and the possibility of programming your own automated search methods. Finally, the shared library, foundation of the unit, will be available for those which would like to develop their own interface. Developpers are invited to contact us through Mulcyber, the software forge hosting the CarthaGene software project.


Since version 0.99, CarthaGène is entirely free and does not require any software key to unlock all available functionnalities. CarthaGène executables are available for Linux (i386), Solaris (2.6) and Windows operating systems. For those interested, a source package is also available. In order to run, CarthaGène also requires the scripting language Tcl/Tk with the [incr Tcl], [incr Tk] and iwidgets extensions to be installed.

CarthaGène includes some fonctionnalities which have been developped thanks to the financial support of the Génoplante project BiZMS1P8. These functionalities allows Carthagène to interact with the GENOPLANTE ® MCQTL software for QTL-mapping in multiple populations and the GENOPLANTE ® BioMercator software for the meta-analysis of QTL detected in independent experiments. These tools are available from Génoplante web site.

Last modified: Tue Oct 5 09:57:39 CEST 2004